Traditionally, cardigans were made of wool but can now be made of cotton , synthetic fibers , or any combination thereof. The term originally referred only to a knitted sleeveless vest , but expanded to other types of garment over time.
Late in 2010 the peer-reviewed Journal of Obesity published a meta-analysis of studies testing the garcinia as a weight loss aid. Of the 23 trials they identified, 12 were methodologically sound enough to include in their analysis.
The analysis revealed that some statistically significant weight loss occurred, but the magnitude of the effect is small and the clinical relevance is uncertain. They also found that gastrointestinal adverse events were twice as likely in the hydroxycitric acid group as in the placebo group.
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